Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.66 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.60 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.60 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | DTYMK | P23919 | 4/20 | 0.60 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.58 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13127042 | 1.00 | POLB (0.69) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL13111573 | 1.00 | POLB (0.69) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL10055622 | 1.00 | POLB (0.69) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL703733 | 0.90 | POLB (0.80) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL18785117 | 0.90 | POLB (0.80) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL78250 | 0.90 | POLB (0.80) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL889289 | 0.90 | POLB (0.80) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL14471000 | 0.90 | POLB (0.80) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL5044161 | 0.90 | POLB (0.80) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL29702495 | 0.90 | POLB (0.80) | POLBP2RY1ENPP1P2RY2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9702001-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20150307933-A1 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
| US-8906612-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| WO-2012027625-A2 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |