Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 9/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 9/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 9/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 9/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10131058 | 0.88 | BMPR1B (0.41) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL10130965 | 0.85 | KCNH2 (0.46) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL10130975 | 0.85 | KCNH2 (0.46) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL9950595 | 0.85 | KCNH2 (0.46) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL10131044 | 0.84 | BMPR1B (0.43) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL2712940 | 0.84 | BMPR1B (0.43) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL9951390 | 0.84 | BMPR1B (0.43) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL16215120 | 0.84 | BMPR1B (0.43) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL2715051 | 0.84 | BMPR1B (0.41) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL10131034 | 0.82 | PRKDC (0.40) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906913-B2 | Azabicyclohexanes | PANACEA BIOTEC LIMITED (IN) | 2014-12-09 | — | — | US | disclosed |