Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12276720 | 0.87 | GPR119 (0.58) | GPR119CYP2C9 | |
| SCHEMBL16281146 | 0.87 | GPR119 (0.59) | GPR119CYP2C9 | |
| SCHEMBL16281323 | 0.83 | GPR119 (0.70) | GPR119CYP2C9 | |
| SCHEMBL12276324 | 0.81 | GPR119 (0.59) | GPR119CYP2C9 | |
| SCHEMBL12276341 | 0.81 | GPR119 (0.50) | GPR119CYP2C9 | |
| SCHEMBL12276767 | 0.80 | GPR119 (0.58) | GPR119CYP2C9 | |
| SCHEMBL12276659 | 0.77 | GPR119 (0.85) | GPR119 | |
| SCHEMBL10106714 | 0.76 | GPR119 (0.52) | GPR119CYP2C9 | |
| SCHEMBL12276877 | 0.75 | GPR119 (0.69) | GPR119 | |
| SCHEMBL12320705 | 0.75 | GPR119 (0.52) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8907095-B2 | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8907095-B2 | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |