Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12277445 | 1.00 | GPR119 (0.76) | GPR119 | |
| SCHEMBL12320320 | 1.00 | GPR119 (0.76) | GPR119 | |
| SCHEMBL12275869 | 0.90 | GPR119 (0.80) | GPR119 | |
| SCHEMBL16281159 | 0.90 | GPR119 (0.87) | GPR119 | |
| SCHEMBL12320405 | 0.87 | GPR119 (0.68) | GPR119 | |
| SCHEMBL12276715 | 0.87 | GPR119 (0.68) | GPR119 | |
| SCHEMBL12274869 | 0.87 | GPR119 (0.78) | GPR119 | |
| SCHEMBL12320008 | 0.86 | GPR119 (0.74) | GPR119 | |
| SCHEMBL12275710 | 0.86 | GPR119 (0.74) | GPR119 | |
| SCHEMBL12320001 | 0.86 | GPR119 (1.00) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8907095-B2 | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8907095-B2 | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |