Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16281328 | 0.98 | GPR119 (0.79) | GPR119 | |
| SCHEMBL10120533 | 0.98 | GPR119 (0.78) | GPR119 | |
| SCHEMBL10106108 | 0.98 | GPR119 (0.78) | GPR119 | |
| SCHEMBL10106367 | 0.98 | GPR119 (0.78) | GPR119 | |
| SCHEMBL12320068 | 0.97 | GPR119 (0.81) | GPR119 | |
| SCHEMBL16281396 | 0.94 | GPR119 (0.76) | GPR119 | |
| SCHEMBL16281382 | 0.93 | GPR119 (0.68) | GPR119 | |
| SCHEMBL12320292 | 0.93 | GPR119 (0.68) | GPR119 | |
| SCHEMBL12320717 | 0.91 | GPR119 (0.80) | GPR119 | |
| SCHEMBL16281401 | 0.91 | GPR119 (0.82) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8907095-B2 | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8907095-B2 | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |