Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 8/20 | 0.67 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.67 |
| ▸ | CDC7 | O00311 | 2/20 | 0.67 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TLR5 | O60602 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16919875 | 0.81 | CLK1 (0.55) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL30187948 | 0.80 | CLK1 (1.00) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL30093319 | 0.80 | CLK1 (0.67) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL9042411 | 0.80 | CLK1 (0.67) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL12807147 | 0.80 | CLK1 (1.00) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL14090789 | 0.80 | CLK1 (0.61) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL20609579 | 0.80 | CLK1 (0.61) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL14115537 | 0.80 | CLK1 (0.61) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL1322519 | 0.77 | CLK1 (0.58) | CLK1LIMK1CDC7DBF4PIK3CA | |
| SCHEMBL16281240 | 0.76 | LIMK1 (0.65) | LIMK1PIK3CAEGFRCHRM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172057-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| EP-2910555-B1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORP (US) | 2019-03-27 | — | — | EP | disclosed |
| US-9755159-B2 | Organic materials for OLEDs | UNIVERSAL DISPLAY CORPORATION (US) | 2017-09-05 | — | — | US | disclosed |
| US-9502656-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160243085-A1 | SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS | MIDCAP FINANCIAL TRUST | 2016-08-25 | — | — | US | disclosed |
| US-9353126-B2 | Substituted triazoles useful as Axl inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2476679-B1 | Substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC (US) | 2015-10-14 | — | — | EP | disclosed |
| US-20150243893-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-08-27 | — | — | US | disclosed |
| EP-2910555-A1 | Organic electroluminescent materials and devices | Universal Display Corporation (US) | 2015-08-26 | — | — | EP | disclosed |
| US-20150207082-A1 | ORGANIC MATERIALS FOR OLEDS | UNIVERSAL DISPLAY CORPORATION (US) | 2015-07-23 | — | — | US | disclosed |
| US-20150072959-A1 | SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS | MIDCAP FINANCIAL TRUST | 2015-03-12 | — | — | US | disclosed |
| US-8906922-B2 | Substituted triazoles useful as AXl inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2014-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150207082-A1 | ORGANIC MATERIALS FOR OLEDS | OCIAD1, OCIAD2, SLC25A21 | CLK1 4770/4885LIMK1 4180/4885CDC7 1523/4885 |
| US-20230172057-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE | CHRM1, CHRM2, CHRM4 | CLK1 1567/4885LIMK1 1044/4885CDC7 1050/4885 |
| US-20150072959-A1 | SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS | AXL, TYRO3, MERTK | CLK1 1522/4885LIMK1 500/4885CDC7 520/4885 |
| US-20160243085-A1 | SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS | AXL, TYRO3, MERTK | CLK1 1522/4885LIMK1 500/4885CDC7 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.