SCHEMBL16282176

SCHEMBL16282176

c1ccc(-c2cccc3c2sc2c(N(c4ccccc4)c4ccc5c(c4)Oc4cccc6c(N(c7ccccc7)c7cccc8c7sc7c(-c9ccccc9)cccc78)ccc-5c46)cccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.33
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16282166 0.88 ALOX5 (0.31)
SCHEMBL17999920 0.88 KDM4E (0.35) KDM4EMAPK1ATM
SCHEMBL16282183 0.87 ALOX5 (0.33)
SCHEMBL16282175 0.87 ALOX5 (0.31)
SCHEMBL17999924 0.87 KDM4E (0.35) KDM4EMAPK1ATM
SCHEMBL25915615 0.86 ALOX5 (0.39)
SCHEMBL16282148 0.83 PRKDC (0.31) KDM4EMAPK1ATM
SCHEMBL17999929 0.83 KDM4E (0.34) KDM4EMAPK1ATM
SCHEMBL17999933 0.83 KDM4E (0.34) KDM4EMAPK1ATM
SCHEMBL17999918 0.83 KDM4E (0.34) KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9425416-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-23 US disclosed
US-9425416-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-23 US disclosed
US-20140361266-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed
US-20140361266-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed