SCHEMBL16282186

SCHEMBL16282186

c1ccc(N(c2ccc3ccccc3c2)c2ccc3c4c(cccc24)Oc2cc(N(c4ccccc4)c4cccc5c4oc4ccccc45)ccc2-3)cc1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
ALOX5 P09917 1/20 0.31
NPC1 O15118 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17999953 0.97 KDM4E (0.31) KDM4EMAPK1ATMALOX5NPC1
SCHEMBL16282195 0.96 KDM4E (0.33) KDM4EMAPK1ATMALOX5NPC1
SCHEMBL17999919 0.94 ALOX5 (0.34) KDM4EMAPK1ATMALOX5
SCHEMBL16282093 0.94 KDM4E (0.30) KDM4EMAPK1ATMALOX5
SCHEMBL16282156 0.93 ALOX5 (0.34) ALOX5
SCHEMBL17999937 0.91 ALOX5 (0.34) ALOX5
SCHEMBL16282170 0.91
SCHEMBL16282171 0.90 ALOX5 (0.34) ALOX5
SCHEMBL17999955 0.90 KDM4E (0.30) KDM4EMAPK1ATM
SCHEMBL17702185 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9425416-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-23 US disclosed
US-9425416-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-23 US disclosed
US-20140361266-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed
US-20140361266-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed