Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 12/20 | 0.47 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19965699 | 0.85 | KMT2A (0.60) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL19135681 | 0.82 | USP7 (0.41) | KDM4EALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL3203433 | 0.82 | P4HTM (0.53) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL22778670 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL10328712 | 0.79 | KMT2A (0.51) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL27927702 | 0.76 | P4HTM (0.47) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL29108500 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL18745377 | 0.74 | NPC1 (0.38) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL211804 | 0.74 | KMT2A (0.70) | KDM4EALDH1A1L3MBTL1KMT2AP4HTM | |
| SCHEMBL31532327 | 0.74 | KMT2A (0.70) | KDM4EALDH1A1L3MBTL1KMT2AP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783501-B2 | Substituted quinolines as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-10-10 | — | — | US | disclosed |
| US-20140363758-A1 | PATTERN FORMING METHOD, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, MANUFACTURING METHOD OF ELECTRONIC DEVICE USING THE SAME AND ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2014-12-11 | — | — | US | disclosed |