Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19620069 | 1.00 | KCNH2 (0.50) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL17751541 | 1.00 | KCNH2 (0.50) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL16282902 | 1.00 | KCNH2 (0.50) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL16282927 | 0.95 | CYP3A4 (0.54) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL16282930 | 0.95 | CYP3A4 (0.54) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL19620065 | 0.95 | CYP3A4 (0.54) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL19620064 | 0.95 | CYP3A4 (0.54) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL17751539 | 0.95 | CYP3A4 (0.54) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL16282901 | 0.95 | CYP3A4 (0.54) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL16282903 | 0.95 | CYP3A4 (0.54) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160136134-A1 | ANTIVIRAL COMPOUNDS HIGHLY EFFECTIVE AS HCV-NS5A INHIBITOR | AB Pharma Ltd. (CN) | 2016-05-19 | — | — | US | disclosed |
| US-20160136134-A1 | ANTIVIRAL COMPOUNDS HIGHLY EFFECTIVE AS HCV-NS5A INHIBITOR | AB Pharma Ltd. (CN) | 2016-05-19 | — | — | US | disclosed |
| US-20140364429-A1 | ANTIVIRAL COMPOUNDS HIGHLY EFFECTIVE AS HCV-NS5A INHIBITOR | AB Pharma Ltd. (CN) | 2014-12-11 | — | — | US | disclosed |
| US-20140364429-A1 | ANTIVIRAL COMPOUNDS HIGHLY EFFECTIVE AS HCV-NS5A INHIBITOR | AB Pharma Ltd. (CN) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160136134-A1 | ANTIVIRAL COMPOUNDS HIGHLY EFFECTIVE AS HCV-NS5A INHIBITOR | MAVS, HAVCR2, EIF2AK2 | KCNH2 4178/4885CYP3A4 809/4885CYP2C9 1423/4885 |
| US-20140364429-A1 | ANTIVIRAL COMPOUNDS HIGHLY EFFECTIVE AS HCV-NS5A INHIBITOR | MAVS, HAVCR2, EIF2AK2 | KCNH2 4178/4885CYP3A4 809/4885CYP2C9 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.