SCHEMBL16282969

SCHEMBL16282969

c1ccc2c(c1)oc1ccc(-n3c4ccccc4c4cc5c(cc43)sc3ccccc35)cc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KDM4E B2RXH2 3/20 0.36
HPGD P15428 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
GPR3 P46089 1/20 0.34
ATM Q13315 1/20 0.34
AHR P35869 2/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAOA P21397 1/20 0.32
CHRNA7 P36544 1/20 0.31
KCNH2 Q12809 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246316 0.95 MAPT (0.36) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL17246530 0.93 MAPT (0.36) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL16283001 0.93 AHR (0.36) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL24174199 0.91 KDM4E (0.34) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL24519155 0.91 KDM4E (0.31) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL17246559 0.91 KDM4E (0.34) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL14822418 0.90 MAPT (0.36) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL17245943 0.90 AHR (0.36) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL21914709 0.90 ALOX5 (0.39) ATMKCNH2
SCHEMBL17071032 0.90 AHR (0.34) MAPTALDH1A1SMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210104679-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2021-04-08 US disclosed
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-10573839-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed
US-20140364625-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM & HAAS ELECT MAT (KR) 2014-12-11 US disclosed
US-20140364625-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM & HAAS ELECT MAT (KR) 2014-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210104679-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, OR10J3, SLCO2B1 MAPT 971/4885ALDH1A1 931/4885SMN1; SMN2 2944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.