SCHEMBL16282982

SCHEMBL16282982

CC1(C)c2ccccc2-c2cc3c4ccccc4n(-c4ccc5c(c4)c4cc(N(c6ccccc6)c6ccccc6)ccc4n5-c4ccccc4)c3cc21

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14849857 0.97 PGR (0.32) KDM4EATML3MBTL1PGR
SCHEMBL16282966 0.96 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL15583107 0.96 KDM4E (0.37) KDM4EATML3MBTL1PGR
SCHEMBL15582988 0.96 KDM4E (0.37) KDM4EATML3MBTL1PGR
SCHEMBL31649 0.94 KDM4E (0.38) KDM4EATML3MBTL1PGR
SCHEMBL15582977 0.94 PGR (0.31) PGR
SCHEMBL802462 0.94 PGR (0.33) KDM4EATML3MBTL1PGR
SCHEMBL15582882 0.94 KDM4E (0.39) KDM4EATML3MBTL1PGR
SCHEMBL14960742 0.93 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL16675639 0.93 KDM4E (0.38) KDM4EATML3MBTL1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140364625-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM & HAAS ELECT MAT (KR) 2014-12-11 US disclosed
US-20140364625-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM & HAAS ELECT MAT (KR) 2014-12-11 US disclosed