SCHEMBL16284607

SCHEMBL16284607

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-c4ccc5cc(-n6c7cccc8ccc9cccc6c9c87)ccc5c4)n3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK10 P53779 2/20 0.37
MAPK9 P45984 1/20 0.37
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
PDE6D O43924 1/20 0.36
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
NR3C1 P04150 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16284620 0.99 KMT2A (0.40) KMT2AMEN1ALDH1A1KDM4ETP53
SCHEMBL16284587 0.92 CYP1A1 (0.44) KMT2AMEN1ALDH1A1KDM4ETP53
SCHEMBL16284618 0.90 CYP1A1 (0.46) KMT2AMEN1ALDH1A1KDM4ETP53
SCHEMBL16284578 0.90 PDE6D (0.40) KMT2AMEN1ALDH1A1KDM4ETP53
SCHEMBL16284590 0.90 PDE6D (0.40) KMT2AMEN1ALDH1A1KDM4ETP53
SCHEMBL16284606 0.90 PDE6D (0.40) KMT2AMEN1ALDH1A1KDM4ETP53
SCHEMBL16284619 0.89 CYP1A1 (0.48) KMT2AMEN1ALDH1A1KDM4ETP53
SCHEMBL16284626 0.89 MAPK10 (0.47) KMT2ACYP1A2MAPK10MAPK9MAPT
SCHEMBL16284573 0.88 L3MBTL1 (0.40) KMT2AMEN1ALDH1A1KDM4ETP53
SCHEMBL22988904 0.87 MEN1 (0.39) KMT2AMEN1ALDH1A1KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9705093-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-11 US disclosed
US-9705093-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-11 US disclosed
US-20140361268-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed
US-20140361268-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed