SCHEMBL16285697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16285698	0.91	CDK4 (0.48)	CDK4CCND1CCND2CCND3GAA
	SCHEMBL16285681	0.90	FYN (0.56)	CDK4CCND1CCND2CCND3DHFR
	SCHEMBL16285670	0.89	NTRK1 (0.50)	MAPTHPGDCDK4CCND1CCND2
	SCHEMBL16285671	0.88	MEN1 (0.53)	MAPTHPGDSMN1; SMN2CDK4CCND1
	SCHEMBL16285674	0.88	CDK4 (0.50)	CDK4CCND1CCND2CCND3FYN
	SCHEMBL16285684	0.86	CDK4 (0.45)	MAPTHPGDCDK4CCND1CCND2
	SCHEMBL16285682	0.86	CDK4 (0.45)	MAPTHPGDCDK4CCND1CCND2
	SCHEMBL16285709	0.85	HTR1A (0.46)	CDK4CCND1CCND2CCND3JAK2
	SCHEMBL16285675	0.85	EGFR (0.49)	CDK4CCND1CCND2CCND3FYN
	SCHEMBL16285701	0.85	CDK4 (0.47)	CDK4CCND1CCND2CCND3FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.