Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113361 | 0.81 | KDM4E (0.40) | PIM3TOP1KDM4EHPGDALDH1A1 | |
| SCHEMBL1628321 | 0.79 | KCNH2 (0.38) | PIM3PIM1TOP1KDM4EHPGD | |
| SCHEMBL1552485 | 0.79 | ALDH1A1 (0.37) | PIM3TOP1KDM4EHPGDALDH1A1 | |
| SCHEMBL1558105 | 0.79 | ALDH1A1 (0.37) | PIM3TOP1KDM4EHPGDALDH1A1 | |
| SCHEMBL1628647 | 0.75 | KDM4E (0.33) | KDM4EHPGDALDH1A1HSD17B10POLB | |
| SCHEMBL1629770 | 0.75 | KDM4E (0.37) | PIM3TOP1KDM4EHPGDALDH1A1 | |
| SCHEMBL1556635 | 0.75 | ALDH1A1 (0.45) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL7017055 | 0.73 | KDM4E (0.44) | KDM4EHPGDALDH1A1HSD17B10POLB | |
| SCHEMBL6509717 | 0.72 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL7519435 | 0.72 | KDM4E (0.34) | KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4669607-B2 | — | — | 2011-04-13 | — | — | JP | claimed |
| JP-2001516756-A | — | — | 2001-10-02 | — | — | JP | claimed |
| EP-1015445-A1 | ANTIMICROBIAL QUINOLONES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2000-07-05 | — | — | EP | claimed |
| WO-1999014214-A1 | ANTIMICROBIAL QUINOLONES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-25 | — | — | WO | claimed |