Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16286904 | 1.00 | TSHR (0.60) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL1403767 | 0.98 | TSHR (0.57) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL1501544 | 0.95 | TSHR (0.53) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL19019800 | 0.88 | TSHR (0.60) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL845751 | 0.87 | TSHR (0.53) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL19019793 | 0.86 | TSHR (0.57) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL29733357 | 0.85 | TSHR (0.66) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL12623866 | 0.81 | TSHR (0.64) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL17440407 | 0.81 | TSHR (0.59) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL19019805 | 0.81 | TSHR (0.54) | TSHRTHRBHTTPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9109072-B2 | Curable composition and uses thereof | SHOWA DENKO K.K. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20140378571-A1 | CURABLE COMPOSITION AND USES THEREOF | SHOWA DENKO K.K. (JP) | 2014-12-25 | — | — | US | disclosed |
| EP-2813521-A1 | CURABLE COMPOSITION AND APPLICATION THEREFOR | Showa Denko K.K. (JP) | 2014-12-17 | — | — | EP | disclosed |