SCHEMBL1403767

SCHEMBL1403767

C=C(C)C(=O)OCCCCC(CC)(CC)O[SiH3]

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
THRB P10828 1/20 0.46
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.33
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16286904 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16286642 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1501544 0.97 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL845751 0.88 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19019793 0.87 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19019800 0.86 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29733357 0.83 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19019805 0.82 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL17440407 0.82 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL136591 0.80 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545747-B2 Method, kit, and device for preparing glycan from glycoprotein NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2026-02-10 US disclosed
EP-3896074-B1 METHOD, KIT, AND DEVICE FOR PREPARING GLYCAN FROM GLYCOPROTEIN AIST (JP) 2023-10-25 EP disclosed
EP-4009108-A1 EXTERNAL ADDITIVE PARTICLES, TONER, AND METHOD FOR PRODUCING EXTERNAL ADDITIVE PARTICLES Canon Kabushiki Kaisha (JP) 2022-06-08 EP disclosed
CN-114578665-A External additive particle, toner, and method for producing external additive particle 佳能株式会社 2022-06-03 CN disclosed
US-20220171305-A1 EXTERNAL ADDITIVE PARTICLES, TONER, AND METHOD FOR PRODUCING EXTERNAL ADDITIVE PARTICLES CANON KABUSHIKI KAISHA (JP) 2022-06-02 US disclosed
US-20220128920-A1 EXTERNAL ADDITIVE PARTICLE AND TONER CANON KABUSHIKI KAISHA (JP) 2022-04-28 US disclosed
EP-3989003-A1 EXTERNAL ADDITIVE PARTICLE AND TONER CANON KABUSHIKI KAISHA (JP) 2022-04-27 EP disclosed
CN-114384776-A External additive particles and toner 佳能株式会社 2022-04-22 CN disclosed
US-20220017648-A1 Method, Kit, and Device for Preparing Glycan from Glycoprotein SUMITOMO BAKELITE CO., LTD. (JP) 2022-01-20 US disclosed
EP-3896074-A1 METHOD, KIT, AND DEVICE FOR PREPARING GLYCAN FROM GLYCOPROTEIN NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2021-10-20 EP disclosed
US-20100062475-A1 PARTICLE FOR MEDICAL USE, PARTICLE FOR ANLAYSIS AND METHOD OF PRODUCING THE SAME SUMITOMO BAKELITE COMPANY (JP) 2010-03-11 US disclosed
US-20090140284-A1 Transparent Inorganic Oxide Dispersion and Iorganic Oxide Particle-Containing Resin Composition, Composition for Sealing Light Emitting Element and Light Emitting element, Hard Coat Film and Optical Functional Film and Optical Component, and Method for Producing Inorganic Oxide Pariticle-Containing Resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2009-06-04 US disclosed
EP-2026849-A2 CURABLE HYDROPHILIC COMPOSITIONS 3M Innovative Properties Company (US) 2009-02-25 EP disclosed
US-20090025608-A1 FLUOROCHEMICAL URETHANE COMPOUNDS HAVING PENDENT SILYL GROUPS 3M INNOVATIVE PROPERTIES COMPANY 2009-01-29 US disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 EP disclosed
WO-2008060677-A2 CURABLE HYDROPHILIC COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-05-22 WO disclosed
US-20070275042-A1 CURABLE HYDROPHILIC COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2007-11-29 US disclosed
US-20070260008-A1 Silica-Containing Silicone Resin Composition and Its Molded Product NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2007-11-08 US disclosed
US-6559224-B1 A process for producing a polyorganosiloxane latex comprising the step of preparing a polymerized paste by polymerizing a paste which contains at least a cyclic organosiloxane, a surface active agent, an initiator, and water, and a graft MITSUBISHI RAYON CO., LTD. (JP) 2003-05-06 US disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545747-B2 Method, kit, and device for preparing glycan from glycoprotein FUT7, FUT4, SIGLEC7 TSHR 565/4885THRB 388/4885POLB 3362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.