SCHEMBL16288295

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16288297	1.00	CYP1A2 (0.51)	CYP1A2CYP2C9CYP2C19HTTNOD1
	SCHEMBL16288581	0.88	CYP1A2 (0.50)	CYP1A2CYP2C9CYP2C19HTTACE
	SCHEMBL16288582	0.88	CYP1A2 (0.50)	CYP1A2CYP2C9CYP2C19HTTACE
	SCHEMBL18661581	0.86	ACE (0.48)	CYP1A2CYP2C9CYP2C19HTTNOD1
	SCHEMBL1455923	0.85	CYP1A2 (0.61)	CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
	SCHEMBL1455920	0.85	CYP1A2 (0.61)	CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
	SCHEMBL16288666	0.85	CYP1A2 (0.50)	CYP1A2CYP2C9CYP2C19HTTNOD1
	SCHEMBL16288665	0.85	CYP1A2 (0.50)	CYP1A2CYP2C9CYP2C19HTTNOD1
	SCHEMBL23140735	0.84	ACE (0.51)	CYP1A2CYP2C9CYP2C19HTTACE
	SCHEMBL15083163	0.84	ACE (0.51)	CYP1A2CYP2C9CYP2C19HTTACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.