Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL2305257 | 1.00 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL29253778 | 0.90 | KMT2A (0.86) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL28086669 | 0.88 | ALOX15 (0.76) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL27392531 | 0.87 | KMT2A (0.91) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL27392525 | 0.87 | KMT2A (0.91) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL411170 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL1332116 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL411588 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL711605 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL411575 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108004203-A | A kind of culture medium and its method for induced multi-potent stem cell | 广东艾时代生物科技有限责任公司 | 2018-05-08 | — | — | CN | disclosed |
| US-20140205593-A1 | MONOVALENT ANTIBODY FRAGMENTS USEFUL AS THERAPEUTICS | GENENTECH, INC. (US) | 2014-07-24 | — | — | US | disclosed |
| CN-103710301-A | Application of mouse embryo liver stroma cell KM3 as human embryo stem cell feeder layer cell | UNIV JIANGSU | 2014-04-09 | — | — | CN | disclosed |
| US-20110200596-A1 | MONOVALENT ANTIBODY FRAGMENTS USEFUL AS THERAPEUTICS | GENENTECH, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-7927583-B2 | Receptor based antagonists and methods of making and using | REGENERON PHARMACEUTICALS, INC. (US) | 2011-04-19 | — | — | US | disclosed |
| US-20090010879-A1 | Receptor Based Antagonists and Methods of Making and Using | REGENERON PHARMACEUTICALS, INC. | 2009-01-08 | — | — | US | disclosed |
| US-7417134-B2 | IL-1 receptor based cytokine traps and method of using | REGENERON PHARMACEUTICALS, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-7083949-B2 | Receptor based antagonists and methods of making and using | REGENERON PHARMACEUTICALS, INC. (US) | 2006-08-01 | — | — | US | disclosed |
| US-20050222033-A1 | Receptor based antagonists and methods of making and using | REGENERON PHARMACEUTICALS, INC. | 2005-10-06 | — | — | US | disclosed |
| CN-1655814-A | Selective antibody of tumor necrosis factor related apoptosis inducing ligand receptor and use thereof | UAB RESEARCH FOUNDATION (US) | 2005-08-17 | — | — | CN | disclosed |
| US-6927044-B2 | IL-1 receptor based cytokine traps | REGENERON PHARMACEUTICALS, INC. (US) | 2005-08-09 | — | — | US | disclosed |
| CN-1630516-A | Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents | UAB RESEARCH FOUNDATION (US) | 2005-06-22 | — | — | CN | disclosed |
| US-20030143697-A1 | Receptor based antagonists and methods of making and using | REGENERON PHARMACEUTICALS, INC. | 2003-07-31 | — | — | US | disclosed |
| US-20030104567-A1 | Receptor based antagonists and methods of making and using | REGENERON PHARMACEUTICALS, INC. | 2003-06-05 | — | — | US | disclosed |
| US-20020164690-A1 | Receptor based antagonists and methods of making and using | STAHL NEIL (US) | 2002-11-07 | — | — | US | disclosed |
| US-20020012962-A1 | RECEPTOR BASED ANTAGONISTS AND METHODS OF MAKING AND USING | REGENERON PHARMACEUTICALS, INC. | 2002-01-31 | — | — | US | disclosed |
| US-5844099-A | Cytokine antagonists | REGENERON PHARMACEUTICALS, INC. (US) | 1998-12-01 | — | — | US | disclosed |