Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132 | 0.83 | MYC (0.47) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2870 | 0.83 | MYC (0.47) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2687 | 0.82 | MYC (0.45) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2432 | 0.81 | MYC (0.45) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL8065614 | 0.81 | MYC (0.45) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2174 | 0.81 | MYC (0.45) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2208 | 0.81 | MYC (0.48) | MYCWDR5MMEFFAR1AKR1B1 | |
| Hydrochloric Acid SCHEMBL15663201 | 0.81 | MYC (0.45) | MYCWDR5MMEFFAR1AKR1B1 | |
| Hydrochloric Acid SCHEMBL3526296 | 0.81 | MYC (0.45) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2693 | 0.79 | ITGB1 (0.46) | MYCWDR5MMEFFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |