SCHEMBL1629133

SCHEMBL1629133

O=C(O)Cc1cccc2cc3ccccc3cc12

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.70
AKR1B1 P15121 3/20 0.52
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 4/20 0.49
GAA P10253 2/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
CYP1A2 P05177 2/20 0.46
GLA P06280 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP2C19 P33261 1/20 0.46
CXCL8 P10145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706153 1.00 TDP1 (0.70) TDP1AKR1B1KDM4EALDH1A1GAA
Water SCHEMBL27719689 0.98 TDP1 (0.68) TDP1AKR1B1KDM4EALDH1A1GAA
SCHEMBL28972751 0.98 TDP1 (0.68) TDP1AKR1B1KDM4EALDH1A1GAA
SCHEMBL1567996 0.85 TDP1 (0.50) TDP1KDM4EALDH1A1GAAMEN1
SCHEMBL26628647 0.84 TDP1 (0.49) TDP1KDM4EALDH1A1GAAMEN1
SCHEMBL2243225 0.83 TDP1 (0.49) TDP1KDM4EALDH1A1GAAMEN1
SCHEMBL29607554 0.82 TDP1 (1.00) TDP1AKR1B1KDM4EALDH1A1GAA
SCHEMBL27710793 0.82 TDP1 (1.00) TDP1AKR1B1KDM4EALDH1A1GAA
SCHEMBL35925 0.82 TDP1 (1.00) TDP1AKR1B1KDM4EALDH1A1GAA
SCHEMBL11635573 0.82 L3MBTL1 (0.50) TDP1KDM4EALDH1A1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107722146-B Method for producing solid polyaluminoxane composition 三井化学株式会社 2021-02-26 CN claimed
CN-107722148-B Solid polyaluminoxane composition, catalyst for olefin polymerization, and method for producing olefin polymer 三井化学株式会社 2021-06-08 CN disclosed
CN-107722146-B Method for producing solid polyaluminoxane composition 三井化学株式会社 2021-02-26 CN disclosed
EP-1523974-B1 Composition for rapid disintegrating tablet in oral cavity FUJI CHEM IND CO LTD (JP) 2018-08-08 EP disclosed
EP-1674083-B1 TABLET QUICKLY DISINTEGRATING IN ORAL CAVITY FUJI CHEM IND CO LTD (JP) 2018-08-01 EP disclosed
US-8647668-B2 Tablet quickly disintegrating in oral cavity FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-02-11 US disclosed
CN-1856298-B Tablets rapidly disintegrating in oral cavity FUJI CHEM IND CO LTD 2013-04-10 CN disclosed
US-8349361-B2 Composition for rapid disintegrating tablet in oral cavity FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2013-01-08 US disclosed
US-20110091546-A1 COMPOSITION FOR RAPID DISINTEGRATING TABLET IN ORAL CAVITY FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2011-04-21 US disclosed
US-7838033-B2 Composition for rapid disintegrating tablet in oral cavity FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-23 US disclosed
CN-100438914-C Composition for intraorally rapidly disintegrating tablet FUJI CHEM IND CO LTD (JP) 2008-12-03 CN disclosed
US-20070275058-A1 Tablet Quickly Disintegrating in Oral Cavity FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-11-29 US disclosed
CN-1856298-A Tablets rapidly disintegrating in oral cavity FUJI CHEM IND CO LTD (JP) 2006-11-01 CN disclosed
CN-1856328-A Composition for intraorally rapidly disintegrating tablet FUJI CHEM IND CO LTD (JP) 2006-11-01 CN disclosed
EP-1674083-A1 TABLET QUICKLY DISINTEGRATING IN ORAL CAVITY FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2006-06-28 EP disclosed
US-20050106240-A1 Composition for rapid disintegrating tablet in oral cavity FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-05-19 US disclosed
EP-1523974-A1 Composition for rapid disintegrating tablet in oral cavity FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-04-20 EP disclosed