Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247427 | 0.96 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL16291088 | 0.92 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL31115218 | 0.91 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL1108022 | 0.87 | THRB (0.44) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL31300058 | 0.85 | TSHR (0.46) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL8925191 | 0.85 | TSHR (0.46) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL6046880 | 0.85 | TSHR (0.46) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL7209197 | 0.85 | THRB (0.43) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL3247446 | 0.85 | TSHR (0.48) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL13528558 | 0.83 | THRB (0.42) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140370432-A1 | Carrier Resins With Improved RH Sensitivity | XEROX CORPORATION | 2014-12-18 | — | — | US | disclosed |