Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL28049628 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28920266 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL676113 | 0.96 | — | — | |
| SCHEMBL1904 | 0.95 | — | — | |
| SCHEMBL2058760 | 0.95 | CA5A (0.46) | — | |
| SCHEMBL126970 | 0.95 | — | — | |
| Methyl Alcohol SCHEMBL23421569 | 0.91 | — | — | |
| SCHEMBL20533683 | 0.91 | — | — | |
| SCHEMBL6917272 | 0.91 | — | — | |
| SCHEMBL20533648 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952059-B2 | Acetyl L-carnitine for the preparation of a medicament for the prevention of painful peripheral neuropathy in patients with type 2 diabetes | Sigma-Tau Industrie Faramceutiche Riunite S.p.A. (IT) | 2015-02-10 | — | — | US | claimed |
| US-20140024712-A1 | ACETYL L-CARNITINE FOR THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION OF PAINFUL PERIPHERAL NEUROPATHY IN PATIENTS WITH TYPE 2 DIABETES | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2014-01-23 | — | — | US | claimed |
| US-8569366-B2 | Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2013-10-29 | — | — | US | claimed |
| EP-3601471-A1 | ANTI-FREEZE ANTI-CORROSION CONCENTRATES | BASF SE (DE) | 2020-02-05 | — | — | EP | disclosed |
| CN-110446768-A | Antifreeze anticorrosion concentrate | BASF SE | 2019-11-12 | — | — | CN | disclosed |
| CN-105814092-B | Composition for hydrophilic cured product | 三井化学株式会社 | 2018-09-21 | — | — | CN | disclosed |
| CN-107430213-A | Hydrophilic optical feature monofilm and its layered product | 三井化学株式会社 | 2017-12-01 | — | — | CN | disclosed |
| US-8454854-B2 | Glycerin-containing antifreezing agent concentrates with corrosion protection | BASF SE (DE) | 2013-06-04 | — | — | US | disclosed |
| US-20130105407-A1 | GLYCERIN-CONTAINING ANTIFREEZING AGENT CONCENTRATES WITH CORROSION PROTECTION | KORMANN CLAUDIUS (DE) | 2013-05-02 | — | — | US | disclosed |
| US-20110163260-A1 | GLYCERIN-CONTAINING ANTIFREEZING AGENT CONCENTRATES WITH CORROSION PROTECTION | BASF AG (DE) | 2011-07-07 | — | — | US | disclosed |
| CN-101128558-B | Antifreeze concentrates comprising glycerine with corrosion protection | BASF AG | 2011-06-29 | — | — | CN | disclosed |
| US-7927505-B2 | preparing from superconcentrates; also monohydric, dihydric, trihydric and poly alcohols other than glycerol, | BASF AKTIENGESELLSCHAFT (DE) | 2011-04-19 | — | — | US | disclosed |
| US-20080149883-A1 | Glycerin-Containing Antifreezing Agent Concentrates With Corrosion Protection | BASF AKIENGESELLSCHAFT (DE) | 2008-06-26 | — | — | US | disclosed |
| CN-101128558-A | Antifreeze concentrates comprising glycerine with corrosion protection | BASF AG (DE) | 2008-02-20 | — | — | CN | disclosed |
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |