Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 11/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16342948 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ACEACE2PRCPTSHR | |
| SCHEMBL19465510 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ACEACE2PRCPTSHR | |
| SCHEMBL15037156 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ACEACE2PRCPTSHR | |
| SCHEMBL15037148 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ACEACE2PRCPTSHR | |
| SCHEMBL16380213 | 0.98 | L3MBTL1 (0.42) | L3MBTL1ACEACE2PRCPTSHR | |
| SCHEMBL16305832 | 0.96 | ITGB1 (0.39) | L3MBTL1ACEACE2PRCPS1PR5 | |
| SCHEMBL16305381 | 0.96 | ITGB1 (0.39) | L3MBTL1ACEACE2PRCPS1PR5 | |
| SCHEMBL16305544 | 0.96 | ITGB1 (0.39) | L3MBTL1ACEACE2PRCPS1PR5 | |
| SCHEMBL17834429 | 0.94 | ACE (0.41) | L3MBTL1ACEACE2PRCPTSHR | |
| SCHEMBL16343394 | 0.93 | ACE (0.46) | L3MBTL1ACEACE2PRCPITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | Receptos, Inc. (US) | 2016-04-20 | — | — | EP | disclosed |
| WO-2014201172-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2014-12-18 | — | — | WO | disclosed |