SCHEMBL1629606

SCHEMBL1629606

COc1ccc2c(c1)C(C)(C)C1(C=Cc3c(ccc4ccccc34)O1)N2C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.56
KDM4E B2RXH2 7/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
THRB P10828 5/20 0.56
GAA P10253 5/20 0.56
LMNA P02545 5/20 0.56
HTT P42858 4/20 0.56
ALDH1A1 P00352 4/20 0.56
HPGD P15428 4/20 0.56
RECQL P46063 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
ALOX12 P18054 2/20 0.56
MAPK1 P28482 2/20 0.56
POLB P06746 1/20 0.56
PKM P14618 2/20 0.47
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
PLIN1 O60240 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29786745 1.00 MAPT (0.56) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL14552807 0.87 MAPT (0.65) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL8680627 0.86 MAPT (0.49) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL8681163 0.85 MAPT (0.48) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL1894170 0.85 MAPT (0.63) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL29931020 0.85 MAPT (0.63) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL29848328 0.85 MAPT (0.63) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL8682556 0.85 MEN1 (0.52) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL8682376 0.84 SMN1; SMN2 (0.49) MAPTKDM4ESMN1; SMN2THRBGAA
SCHEMBL10418850 0.84 MAPT (0.46) MAPTKDM4ESMN1; SMN2THRBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11359136-B2 Colorimetric indicators for photocurable sealants THE BOEING COMPANY (US) 2022-06-14 US claimed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-11359136-B2 Colorimetric indicators for photocurable sealants THE BOEING COMPANY (US) 2022-06-14 US disclosed
US-11061259-B2 Plural element composite materials, methods for making and using the same SEGAN INDUSTRIES, INC. (US) 2021-07-13 US disclosed
CN-106928640-B Strain gauge polymers comprising photochromic colorants 施乐公司 2021-06-01 CN disclosed
US-10747029-B2 Flash imaging devices, methods for making and using the same SEGAN INDUSTRIES, INC. (US) 2020-08-18 US disclosed
US-10381134-B2 Strain gauge polymer comprising photochromic colorant XEROX CORPORATION (US) 2019-08-13 US disclosed
US-10381134-B2 Strain gauge polymer comprising photochromic colorant XEROX CORPORATION (US) 2019-08-13 US disclosed
US-20190179175-A1 Flash imaging devices, methods for making and using the same SEGAN INDUSTRIES, INC. 2019-06-13 US disclosed
US-10143640-B2 Fluorescence plaque-disclosant for detecting dental plaque FLOSS MY HEART, LLC (US) 2018-12-04 US disclosed
US-10054805-B2 Flash imaging devices, methods for making and using the same SEGAN INDUSTRIES, INC. (US) 2018-08-21 US disclosed
US-7050387-B2 Optical storage medium VICTOR COMPANY OF JAPAN, LTD. (JP) 2006-05-23 US disclosed
US-7041332-B2 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-05-09 US disclosed
US-20040008612-A1 Optical storage medium RAKUTEN GROUP, INC. (JP) 2004-01-15 US disclosed
EP-1179558-A1 METHOD OF MODIFYING SURFACE LAYER OF MOLDED RESIN AND APPARATUS FOR MODIFYING SURFACE LAYER OF MOLDED RESIN Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2002-02-13 EP disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10381134-B2 Strain gauge polymer comprising photochromic colorant CABLES1, MAPK11, MARK4 MAPT 358/4885KDM4E 1163/4885SMN1; SMN2 1794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.