Sugi Predict

Sugi Predict / Targets / CABLES1

CABLES1

CDK5 and ABL1 enzyme substrate 1 · Q8TDN4 · CABLES1 on Sugi Atlas →

0 patent compounds predicted against CABLES1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to CABLES1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome PHASE3COMPLETED
Selective Treatment According to Molecular Subtype of Prostate Cancer PHASE2UNKNOWN
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations EARLY_PHASE1COMPLETED
Study of Metabolic Modifications in Children With Noonan Syndrome nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
A Retrospective Study to Determine the Incidence of NTRK Fusions. NTRK Study nanCOMPLETED
GARM II: A Study on the Genetics of Age-related Maculopathy nanACTIVE_NOT_RECRUITING
NTRK 1,2,3 Rearrangements in Patients With Solid Tumors nanACTIVE_NOT_RECRUITING
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy nanCOMPLETED
Genetic Evaluation of NF1 and Scoliosis Patients nanCOMPLETED
Molecular Phenotype Changes and Personalized Treatment for CRPC nanUNKNOWN
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization nanCOMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children nanCOMPLETED
Interest of PHARMaceutical Conciliation to Understand Drug Interactions, Phytotherapy, and Targeted Therapies in Chronic Myeloid Leukemia nanRECRUITING
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia nanRECRUITING
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Comparative 2-D Tumor Analysis in Familial Gliomas nanCOMPLETED
Molecular Analysis of Thoracic Malignancies nanENROLLING_BY_INVITATION
Genetic Aspects of Neurologic and Psychiatric Disorders nanCOMPLETED
Detection of EGFR Mutation in Malignant Pleural Effusion of Lung Cancer Patients and Cancer Cell Lines Establishment nanUNKNOWN
Value of MicroRNA30a in Philadelphia Positive Leukemic Patients nanUNKNOWN
Aberrant Gene Expression Prostate Carcinoma nanACTIVE_NOT_RECRUITING
Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA nanRECRUITING
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia nanUNKNOWN
Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children nanCOMPLETED
Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies nanRECRUITING
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a CABLES1 binder may also engage these)

ProteinNameSimilarity
Q9ESJ1 — 1.000 Q9ESJ1 →
Q6S6U0 — 0.993 Q6S6U0 →
Q9UPV7 — 0.993 Q9UPV7 →
Q7XT42 — 0.993 Q7XT42 →
P28925 — 0.992 P28925 →
Q292U2 — 0.992 Q292U2 →
Q92858 — 0.992 Q92858 →
Q9VB11 — 0.992 Q9VB11 →
Q9BTV7 — 0.992 Q9BTV7 →
Q9Z0Y7 — 0.992 Q9Z0Y7 →
Q5U5Q3 — 0.992 Q5U5Q3 →
Q7TN99 — 0.992 Q7TN99 →
P19091 — 0.992 P19091 →
O14512 — 0.992 O14512 →
Q9VVR2 — 0.992 Q9VVR2 →
P93755 — 0.992 P93755 →
Q6PEV8 — 0.992 Q6PEV8 →
PGR Progesterone receptor 0.991 landscape →
O60292 — 0.991 O60292 →
Q6NN85 — 0.991 Q6NN85 →
O97952 — 0.991 O97952 →
O97775 — 0.991 O97775 →
P48435 — 0.991 P48435 →
O97960 — 0.991 O97960 →
O97776 — 0.991 O97776 →
Q9H329 — 0.991 Q9H329 →
Q05536 — 0.991 Q05536 →
Q29MB2 — 0.990 Q29MB2 →
A7X8B3 — 0.990 A7X8B3 →
Q9BQW3 — 0.990 Q9BQW3 →