SCHEMBL1629682

SCHEMBL1629682

CCCc1ccccc1C(=O)OC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
LMNA P02545 2/20 0.70
TSHR P16473 1/20 0.53
GAA P10253 1/20 0.53
HSD17B10 Q99714 3/20 0.52
CFTR P13569 1/20 0.52
KDM4E B2RXH2 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 2/20 0.50
HTT P42858 1/20 0.50
ATM Q13315 1/20 0.50
HIF1A Q16665 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
GLA P06280 1/20 0.47
MAPK1 P28482 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA5A P35218 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875722 1.00 ALDH1A1 (0.70) ALDH1A1LMNATSHRGAAHSD17B10
SCHEMBL10360804 0.90 ALDH1A1 (0.77) ALDH1A1LMNATSHRGAAHSD17B10
SCHEMBL1789262 0.89 ALDH1A1 (0.66) ALDH1A1LMNATSHRGAAHSD17B10
SCHEMBL28106654 0.88 ALDH1A1 (0.64) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL28406804 0.87 ALDH1A1 (0.53) ALDH1A1LMNATSHRHSD17B10KMT2A
SCHEMBL6462771 0.87 ALDH1A1 (0.53) ALDH1A1LMNATSHRHSD17B10KMT2A
SCHEMBL156281 0.86 ALDH1A1 (0.66) ALDH1A1LMNATSHRGAAHSD17B10
SCHEMBL29148965 0.86 ALDH1A1 (0.62) ALDH1A1LMNATSHRKMT2ASMN1; SMN2
SCHEMBL11552750 0.86 ALDH1A1 (0.62) ALDH1A1LMNATSHRKMT2ASMN1; SMN2
SCHEMBL28106172 0.86 ALDH1A1 (0.62) ALDH1A1LMNATSHRKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112442751-B Preparation method and application of coalescent fiber for oil-water separation 中国石油化工股份有限公司 2023-04-11 CN claimed
CN-106187750-B A kind of method that dimethylbenzene liquid phase catalytic oxidation prepares phthalic acid 中国科学院大连化学物理研究所 2019-07-12 CN claimed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
CN-104080824-A Internal electron donors for olefin polymerization catalysts, methods of making and using the same BASF CORP 2014-10-01 CN claimed
CN-201147556-Y Heat-sensitive surface anesthesia plaster XIANG WAN (CN) 2008-11-12 CN claimed
CN-101229145-A Thermosensitive topical anesthesia patch JILIN UNIVERSAL MEDICAL TREAT (CN) 2008-07-30 CN claimed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
CN-113549010-B Preparation and application of compound with AMPK (AMPK) agonistic activity and prodrug thereof 中国科学院上海药物研究所 2023-10-20 CN disclosed
US-20080268354-A1 COLORED PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER USING THE SAME AND METHOD OF PRODUCING COLOR FILTER FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
CN-101229145-A Thermosensitive topical anesthesia patch JILIN UNIVERSAL MEDICAL TREAT (CN) 2008-07-30 CN disclosed
CN-1192022-C Novel compound SMITHKLINE BEECHAM PLC (GB) 2005-03-09 CN disclosed
CN-1183116-C Substituted isoquinoline derivatives, pharmaceutical composition containing same, preparation method and application thereof ʷ��˿�������ȳ�ķ���޹�˾ 2005-01-05 CN disclosed
EP-1339678-A2 EP4 RECEPTOR SELECTIVE AGONISTS IN THE TREATMENT OF OSTEOPOROSIS Pfizer Products Inc. (US) 2003-09-03 EP disclosed
WO-2002042268-A2 EP4 RECEPTOR SELECTIVE AGONISTS IN THE TREATMENT OF OSTEOPOROSIS PFIZER PRODUCTS INC. (US) 2002-05-30 WO disclosed
CN-1255124-A Substituted isoquinoline derivatives and their use as anticonulsants SMITHKLINE BEECHAM PLC (GB) 2000-05-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, MDM2 ALDH1A1 1427/4885LMNA 711/4885TSHR 3370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.