SCHEMBL1629758

SCHEMBL1629758

CCCCC(CC)COCC(O)CN(CCCO)CC(O)COCC(CC)CCCC

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.43
ALDH1A1 P00352 7/20 0.41
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP14 P50281 1/20 0.37
RECQL P46063 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 1/20 0.36
USP2 O75604 1/20 0.35
CA2 P00918 1/20 0.35
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1626697 0.90 CYP3A4 (0.44) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL14278859 0.86 CYP3A4 (0.46) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL17816459 0.82 CYP3A4 (0.43) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL14839899 0.81 ALDH1A1 (0.52) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL101962 0.81 CYP3A4 (0.56) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL9927986 0.79 CYP3A4 (0.45) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL9927958 0.79 CYP3A4 (0.45) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL9927966 0.79 CYP3A4 (0.45) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL9927993 0.79 CYP3A4 (0.45) CYP3A4ALDH1A1TSHRTDP1ATM
SCHEMBL99276 0.79 ALDH1A1 (0.55) CYP3A4ALDH1A1TSHRTDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110093246-A1 Modeling Systems for Consumer Goods STANTON DAVID THOMAS 2011-04-21 US disclosed
US-20080040082-A1 Modeling systems for consumer goods THE PROCTER & GAMBLE COMPANY 2008-02-14 US disclosed
US-20080027575-A1 Modeling systems for health and beauty consumer goods PROCTER & GAMBLE COMPANY, THE 2008-01-31 US disclosed