Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP9 | P55211 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281652 | 1.00 | ELANE (0.48) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL16313183 | 0.89 | ELANE (0.40) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12161875 | 0.88 | ELANE (0.38) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL16297917 | 0.87 | ELANE (0.38) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL8251792 | 0.87 | CTSV (0.50) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL8251272 | 0.87 | CTSV (0.50) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL8246563 | 0.87 | CTSV (0.50) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL16301687 | 0.87 | CTSV (0.45) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL8279962 | 0.86 | ELANE (0.40) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL8278883 | 0.86 | ELANE (0.48) | ELANECTSVCTSLCTSBCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006113942-A2 | METHOD OF INHIBITING CATHEPSIN ACTIVITY | SCHERING CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |