SCHEMBL16299273

SCHEMBL16299273

CC1C(OCCCCCCCCC(=O)O)OC(COC(=O)c2ccccc2)C(OC2OC(COC(=O)c3ccccc3)C(OC(=O)c3ccccc3)C(OC(=O)c3ccccc3)C2OC(=O)c2ccccc2)C1OC(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANTXR2 P58335 3/20 0.43
PTPN1 P18031 9/20 0.42
F11 P03951 2/20 0.41
USP2 O75604 2/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
ELANE P08246 1/20 0.40
TMPRSS2 O15393 1/20 0.39
PDE5A O76074 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
HMGCR P04035 1/20 0.39
CYP1A2 P05177 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
HSPD1 P10809 1/20 0.39
CYP2C9 P11712 1/20 0.39
CA6 P23280 1/20 0.39
TBXAS1 P24557 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19767543 0.96 USP2 (0.42) ANTXR2PTPN1F11USP2MEN1
SCHEMBL10177707 0.94 ANTXR2 (0.46) ANTXR2PTPN1F11USP2MEN1
SCHEMBL16682385 0.90 PTPN1 (0.40) ANTXR2PTPN1F11USP2MEN1
SCHEMBL17850336 0.90 PTPN1 (0.49) ANTXR2PTPN1F11USP2MEN1
SCHEMBL13250753 0.90 PTPN1 (0.49) ANTXR2PTPN1F11USP2MEN1
SCHEMBL10177606 0.90 PTPN1 (0.49) ANTXR2PTPN1F11USP2MEN1
SCHEMBL806155 0.90 PTPN1 (0.49) ANTXR2PTPN1F11USP2MEN1
SCHEMBL15102739 0.90 PTPN1 (0.49) ANTXR2PTPN1F11USP2MEN1
SCHEMBL16299436 0.89 PAX8 (0.41) ANTXR2PTPN1F11USP2MEN1
SCHEMBL18349835 0.89 USP2 (0.44) PTPN1F11USP2MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9370581-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2016-06-21 US disclosed
US-20120136042-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC (US) 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136042-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES LPXN, ZYX, OSTC ANTXR2 2183/4885PTPN1 1551/4885F11 1343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.