Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.36 |
| ▸ | F11 | P03951 | 2/20 | 0.36 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15833428 | 0.97 | PAX8 (0.41) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL16015593 | 0.96 | PAX8 (0.39) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL15833442 | 0.96 | PAX8 (0.39) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL16299436 | 0.95 | PAX8 (0.41) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL16015605 | 0.94 | PAX8 (0.37) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL19767541 | 0.93 | PAX8 (0.38) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL10177676 | 0.92 | PAX8 (0.43) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL19767532 | 0.91 | KMT2A (0.38) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL16351356 | 0.88 | PAX8 (0.38) | PAX8TSHRPRKCAAKT1PTK2 | |
| SCHEMBL13447794 | 0.88 | TSHR (0.47) | PAX8TSHRMEN1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450467-B2 | Carbohydrate conjugates as delivery agents for oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-05-28 | — | — | US | disclosed |
| US-8106022-B2 | Carbohydrate conjugates as delivery agents for oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |