Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821556 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| SCHEMBL8818106 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| Hydrochloric Acid SCHEMBL23174538 | 0.97 | ALDH1A1 (0.42) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| Hydrochloric Acid SCHEMBL23174539 | 0.97 | ALDH1A1 (0.42) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| SCHEMBL8689663 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| SCHEMBL6437798 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| SCHEMBL6439208 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| SCHEMBL27783843 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| Hydrochloric Acid SCHEMBL19900732 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| Hydrochloric Acid SCHEMBL19900791 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRGGT1GRM2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119136797-A | CB1Ligand conjugated compounds and uses thereof | 阿达尔克斯制药有限公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-2183260-B1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS IV | IDENIX PHARMACEUTICALS INC (US) | 2011-06-01 | — | — | EP | disclosed |
| US-7932240-B2 | Phosphadiazine HCV polymerase inhibitors IV | IDENIX PHARMACEUTICALS, INC. (US) | 2011-04-26 | — | — | US | disclosed |
| EP-2183260-A1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS IV | IDENIX Pharmaceuticals, Inc. (US) | 2010-05-12 | — | — | EP | disclosed |
| US-20090081158-A1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS IV | IDENIX PHARMACEUTICALS, INC. (US) | 2009-03-26 | — | — | US | disclosed |
| WO-2009032180-A1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS IV | IDENIX PHARMACEUTICALS, INC. (US) | 2009-03-12 | — | — | WO | disclosed |
| US-5444061-A | Antitumor agents | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |
| WO-1992016512-A1 | ANTI-CANCER COMPOUNDS | BRITISH TECHNOLOGY GROUP PLC (GB) | 1992-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090081158-A1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS IV | POLI, ITPA, POLR2H | ALDH1A1 1722/4885TSHR 3605/4885GGT1 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.