Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 4/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 7/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24184005 | 0.89 | USP2 (0.44) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL28973706 | 0.89 | USP2 (0.44) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL553482 | 0.84 | BCL2 (0.45) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL554664 | 0.84 | BCL2 (0.45) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL28977057 | 0.83 | ENPP2 (0.43) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL19491866 | 0.82 | USP2 (0.47) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL553496 | 0.81 | BCL2 (0.41) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL553495 | 0.81 | BCL2 (0.41) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL31451040 | 0.81 | BCL2L1 (0.46) | USP2CASRENPP2BCL2BCL2L1 | |
| SCHEMBL31450836 | 0.81 | BCL2L1 (0.46) | USP2CASRENPP2BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017251-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | WO | disclosed |