Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20266373 | 0.92 | PTGER4 (0.64) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL763198 | 0.87 | LNPEP (0.62) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL1205232 | 0.84 | LNPEP (0.57) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL2931229 | 0.83 | PTGER4 (0.55) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL23286966 | 0.82 | MAPT (0.58) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL24900104 | 0.82 | LNPEP (0.56) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL26971242 | 0.81 | LNPEP (0.49) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL23273578 | 0.81 | PTGER4 (0.49) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL2014323 | 0.81 | LNPEP (0.56) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL23703820 | 0.81 | KDM4E (0.52) | PTGER4ALDH1A1MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |