SCHEMBL16301403

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)CCCCCCCNC(=O)CCCCCCCNC(=O)CNC(=O)CC[C@H](NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)NCC(=O)NCCCCCCCC(=O)NCCCCCCCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)C(C)C)C(C)C)C(N)=O

nearest known ligand 0.86

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	GRPR	P30550	18/20	0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16301409	0.92	GRPR (0.86)	GRPR
SCHEMBL14864723	0.90	GRPR (0.72)	GRPR
SCHEMBL14864706	0.90	GRPR (0.76)	GRPR
SCHEMBL16301387	0.90	GRPR (0.86)	GRPR
SCHEMBL1250077	0.89	GRPR (0.85)	GRPR
SCHEMBL1618509	0.89	GRPR (0.85)	GRPR
SCHEMBL16301404	0.89	GRPR (0.92)	GRPR
SCHEMBL1252293	0.88	GRPR (0.86)	GRPR
SCHEMBL1618773	0.88	GRPR (0.86)	GRPR
SCHEMBL1251604	0.88	GRPR (0.86)	GRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20120009122-A1	GASTRIN RELEASING PEPTIDE COMPOUNDS	BRACCO IMAGING S.P.A. (IT)	2012-01-12	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20120009122-A1	GASTRIN RELEASING PEPTIDE COMPOUNDS	GRPR, GIPR, CCKBR	GRPR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.