Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733495 | 0.83 | TSHR (0.48) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9606840 | 0.76 | TSHR (0.55) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3685300 | 0.74 | TSHR (0.52) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7711607 | 0.74 | TSHR (0.52) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12951352 | 0.74 | TSHR (0.52) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL23487152 | 0.73 | CTSK (0.43) | CA12CA14CA1CA2HTT | |
| SCHEMBL31362911 | 0.73 | CTSK (0.43) | CA12CA14CA1CA2HTT | |
| SCHEMBL11370272 | 0.72 | TSHR (0.50) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL15827818 | 0.72 | TSHR (0.50) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL11360491 | 0.72 | TSHR (0.50) | TSHRSLC1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012016188-A2 | METHODS AND COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |