Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ESRRG | P62508 | 4/20 | 0.50 |
| ▸ | RRM1 | P23921 | 2/20 | 0.50 |
| ▸ | RRM2 | P31350 | 2/20 | 0.50 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12955481 | 1.00 | KMT2A (0.59) | KMT2AMEN1GAASMN1; SMN2USP2 | |
| SCHEMBL16609588 | 0.88 | KDM4E (0.68) | KMT2AMEN1GAASMN1; SMN2USP2 | |
| SCHEMBL16301933 | 0.79 | GAA (0.59) | KMT2AMEN1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL24000995 | 0.77 | GAA (0.57) | KMT2AGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17452453 | 0.77 | MEN1 (0.58) | KMT2AMEN1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL16355427 | 0.77 | GAA (0.57) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11879906 | 0.77 | GAA (0.57) | KMT2AGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20831090 | 0.77 | KMT2A (0.59) | KMT2AMEN1GAASMN1; SMN2USP2 | |
| SCHEMBL18609410 | 0.77 | KMT2A (0.53) | KMT2AMEN1GAASMN1; SMN2USP2 | |
| SCHEMBL14289011 | 0.77 | GAA (0.62) | KMT2AMEN1GAASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150423-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| US-20200222400-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | JANSSEN PHARMACEUTICA NV (BE) | 2020-07-16 | — | — | US | disclosed |
| US-20170066731-A1 | SMALL MOLECULE FATTY ACID SYNTHASE INHIBITORS | Sanford Burnham Prebys Medical Discovery Institute | 2017-03-09 | — | — | US | disclosed |
| EP-1689807-B1 | NOVEL DENDRITIC POLYMERS HAVING MONOPHOSPHONIC TERMINATIONS, METHOD FOR PREPARING THEM, AND THEIR USE | RHODIA UK LTD (GB) | 2016-08-17 | — | — | EP | disclosed |
| EP-1771548-B1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NAT RECH SCIENT (FR) | 2012-06-27 | — | — | EP | disclosed |
| WO-2010013086-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200222400-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | NLN, CLN6, OTC | KMT2A 2541/4885MEN1 2780/4885GAA 110/4885 |
| US-20170066731-A1 | SMALL MOLECULE FATTY ACID SYNTHASE INHIBITORS | FASN, FADS2, FADS1 | KMT2A 2811/4885MEN1 4759/4885GAA 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.