Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302533 | 0.84 | RXFP1 (0.32) | HPGDKMT2AMEN1ALDH1A1RXFP1 | |
| SCHEMBL16358756 | 0.82 | LMNA (0.31) | HPGDKMT2AALDH1A1RXFP1 | |
| SCHEMBL849970 | 0.81 | PTH1R (0.34) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL851546 | 0.75 | PTH1R (0.45) | ALDH1A1 | |
| SCHEMBL851419 | 0.75 | POLB (0.33) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13064722 | 0.74 | SMN1; SMN2 (0.36) | KMT2AMAPT | |
| SCHEMBL850355 | 0.71 | POLB (0.33) | MAPT | |
| SCHEMBL851027 | 0.70 | MAPK1 (0.34) | KMT2AMAPTALDH1A1 | |
| SCHEMBL851028 | 0.70 | MAPK1 (0.34) | KMT2AMAPTALDH1A1 | |
| SCHEMBL16358336 | 0.69 | PTH1R (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |