Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12725249 | 0.87 | MEN1 (0.43) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1630882 | 0.86 | MEN1 (0.39) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL4112138 | 0.85 | ADORA2A (0.43) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1855064 | 0.85 | MEN1 (0.42) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL13944318 | 0.85 | MEN1 (0.44) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL12724884 | 0.85 | ADORA2A (0.44) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL12725250 | 0.84 | NPC1 (0.42) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1632021 | 0.84 | MAPT (0.43) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1630422 | 0.84 | KDM4E (0.43) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL4112136 | 0.84 | MEN1 (0.42) | MEN1MAPTKMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932270-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2011-04-26 | — | — | US | disclosed |