Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631372 | 0.87 | ROCK2 (0.39) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1856610 | 0.86 | MEN1 (0.38) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1630359 | 0.85 | MEN1 (0.39) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1863296 | 0.83 | MAPT (0.47) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1863294 | 0.82 | MEN1 (0.46) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1855062 | 0.81 | MAPT (0.42) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL12629063 | 0.81 | MAPT (0.42) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL1630794 | 0.77 | GBA1 (0.48) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL1881988 | 0.76 | GBA1 (0.48) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL14195485 | 0.74 | MEN1 (0.46) | MEN1MAPTKMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939534-B2 | e.g. (2-{[2-(3-fluorophenyl)ethyl]amino}-6-piperidyl(3-pyridyl))-N-(3-pyridylmethyl)carboxamide; smooth muscle myosin or non-muscle myosin modulator; hypotensive agent; asthma, chronic obstructive pulmonary disease, bronchoconstrictive disease, glaucoma, pre-menstrual cramps, erectile dysfunction | CYTOKINETICS, INC. (US) | 2011-05-10 | — | — | US | disclosed |