SCHEMBL163049

SCHEMBL163049

C=C1COC(=O)C1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL791435 0.74
SCHEMBL16077515 0.69
SCHEMBL16079424 0.69
SCHEMBL17550621 0.67
SCHEMBL13446089 0.67 SMN1; SMN2 (0.35)
SCHEMBL5407876 0.63 KMT2A (0.38)
SCHEMBL7634600 0.62
SCHEMBL8055082 0.62 SMN1; SMN2 (0.33)
SCHEMBL9305420 0.62
SCHEMBL14028822 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107098807-B Fermentation pathways for the production of levulinic acid, levulinic acid esters, valerolactone, and derivatives thereof 阿泽达公司 2020-07-10 CN claimed
CN-103180279-B Fermentation pathways for the production of levulinic acid, levulinic acid esters, valerolactone, and derivatives thereof ARZEDA CORP. (US) 2016-12-14 CN claimed
US-20130330779-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS AND VALEROLACTONE AND DERIVATIVES THEREOF ARZEDA CORPORATION 2013-12-12 US claimed
EP-2611764-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF Arzeda Corp. (US) 2013-07-10 EP claimed
WO-2012030860-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF ARZEDA CORP. (US) 2012-03-08 WO claimed
CN-108484542-B Methylene butyrolactone diterpenoid compound with hypoglycemic activity and preparation method and application thereof 浙江医药高等专科学校 2021-10-08 CN disclosed
CN-107098807-B Fermentation pathways for the production of levulinic acid, levulinic acid esters, valerolactone, and derivatives thereof 阿泽达公司 2020-07-10 CN disclosed
US-10246727-B2 Fermentation route for the production of levulinic acid, levulinate esters and valerolactone and derivatives thereof ARZEDA CORP. (US) 2019-04-02 US disclosed
US-20170275657-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS AND VALEROLACTONE AND DERIVATIVES THEREOF ARZEDA CORP. 2017-09-28 US disclosed
CN-107098807-A Fermentation path for producing levulic acid, levulinate, valerolactone and its derivative 阿泽达公司 2017-08-29 CN disclosed
CN-103180279-B Fermentation pathways for the production of levulinic acid, levulinic acid esters, valerolactone, and derivatives thereof ARZEDA CORP. (US) 2016-12-14 CN disclosed
US-9309332-B2 Polymerization catalysts, methods and products COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2016-04-12 US disclosed
US-20140058041-A1 POLYMERIZATION CATALYSTS, METHODS AND PRODUCTS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2014-02-27 US disclosed
EP-2611764-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF Arzeda Corp. (US) 2013-07-10 EP disclosed
WO-2012030860-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF ARZEDA CORP. (US) 2012-03-08 WO disclosed