SCHEMBL16305676

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16305979	0.96	L3MBTL1 (0.48)	L3MBTL1ACEACE2
	SCHEMBL20426117	0.96	L3MBTL1 (0.48)	L3MBTL1ACEACE2
	SCHEMBL17834426	0.90	L3MBTL1 (0.47)	L3MBTL1ACEACE2
	SCHEMBL19485713	0.90	L3MBTL1 (0.51)	L3MBTL1ACEACE2
	SCHEMBL16305672	0.89	ACE (0.42)	PPARGPPARAACEHRH2HRH1
	SCHEMBL16305673	0.89	ACE (0.42)	PPARGPPARAACEHRH2HRH1
	SCHEMBL16305678	0.89	ACE (0.42)	PPARGPPARAACEHRH2HRH1
	SCHEMBL16305664	0.89	ACE (0.42)	PPARGPPARAACEHRH2HRH1
	SCHEMBL16306051	0.89	S1PR5 (0.47)	PPARGPPARAHRH2HRH1ITGB1
	SCHEMBL16305381	0.89	ITGB1 (0.39)	L3MBTL1ACEHRH2HRH1ITGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.