SCHEMBL16306233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17834773	0.92	MME (0.39)	MMEANPEPL3MBTL1KIFC1ACE
	SCHEMBL16306215	0.91	RARB (0.40)	MMEANPEPKIFC1
	SCHEMBL17834846	0.91	MME (0.40)	MMEANPEPL3MBTL1KIFC1ACE
	SCHEMBL17834848	0.90	KIFC1 (0.41)	MMEANPEPL3MBTL1KIFC1KLKB1
	SCHEMBL17834902	0.90	MME (0.41)	MMEANPEPL3MBTL1KIFC1KLKB1
	SCHEMBL16306224	0.90	MME (0.46)	MMEANPEPACECPA1ACE2
	SCHEMBL17834747	0.89	ITGB1 (0.44)	KLKB1
	SCHEMBL16305971	0.89	ITGB1 (0.44)	KLKB1
	SCHEMBL16305982	0.89	ITGB1 (0.41)	MMEANPEPKLKB1
	SCHEMBL19485659	0.89	MME (0.41)	MMEANPEPL3MBTL1KLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.