Sugi Predict

Sugi Predict / Targets / KIFC1

KIFC1

Kinesin-like protein KIFC1 · Q9BW19 · KIFC1 on Sugi Atlas →

5,390 patent compounds predicted against KIFC1, 2,328 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4827795 SCHEMBL4827795 0.54 13/20
SCHEMBL4829753 SCHEMBL4829753 0.50 13/20
SCHEMBL4829761 SCHEMBL4829761 0.50 13/20
SCHEMBL4831455 SCHEMBL4831455 0.57 12/20
SCHEMBL4831637 SCHEMBL4831637 0.51 11/20
SCHEMBL4625569 SCHEMBL4625569 0.43 11/20
SCHEMBL4829763 SCHEMBL4829763 0.51 9/20
SCHEMBL4829768 SCHEMBL4829768 0.51 9/20
SCHEMBL2320863 SCHEMBL2320863 0.49 9/20
SCHEMBL2224717 SCHEMBL2224717 0.44 9/20
SCHEMBL4824397 SCHEMBL4824397 0.60 8/20
SCHEMBL4827800 SCHEMBL4827800 0.58 8/20
SCHEMBL4827802 SCHEMBL4827802 0.58 8/20
SCHEMBL1300650 SCHEMBL1300650 0.53 8/20
SCHEMBL4829612 SCHEMBL4829612 0.51 8/20
SCHEMBL4829625 SCHEMBL4829625 0.51 8/20
SCHEMBL4364821 SCHEMBL4364821 0.47 8/20
SCHEMBL4369873 SCHEMBL4369873 0.47 8/20
SCHEMBL4369999 SCHEMBL4369999 0.47 8/20
SCHEMBL4364912 SCHEMBL4364912 0.46 8/20

Clinical trials — most relevant to KIFC1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Pembrolizumab (MK-3475) in MM Patients With Residual Disease PHASE2COMPLETED
Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel PHASE1COMPLETED
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype EARLY_PHASE1COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Progressive Familial Intrahepatic Cholestasis in Indian Children - Establishing an Indian PFIC Registry nanUNKNOWN
Registry and Natural History of Epilepsy-Dyskinesia Syndromes nanRECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS nanRECRUITING
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
PCD New Gene Discovery nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Structural Validity and Inter-rater Reliabitiliy of the Ataxia Trunk, Lower And Upper Extremity Scale (ATLAS) nanNOT_YET_RECRUITING
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases nanCOMPLETED
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics nanCOMPLETED
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases nanCOMPLETED
Shanghai High Myopia Study nanRECRUITING
Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay nanNOT_YET_RECRUITING
Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders nanRECRUITING
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies nanRECRUITING
Clinical Registry Investigating Bardet-Biedl Syndrome nanRECRUITING
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes nanRECRUITING
Gait in Rare Diseases nanCOMPLETED
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN
Spastic Paraplegia - Centers of Excellence Research Network nanRECRUITING
Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a KIFC1 binder may also engage these)

ProteinNameSimilarity
Q9QWT9 — 1.000 Q9QWT9 →
Q60443 — 1.000 Q60443 →
Q5XI63 — 1.000 Q5XI63 →
O35231 — 0.993 O35231 →
Q9BVG8 — 0.992 Q9BVG8 →
B7ZNG0 — 0.989 B7ZNG0 →
Q4R918 — 0.987 Q4R918 →
Q2M1P5 — 0.987 Q2M1P5 →
O08672 — 0.987 O08672 →
Q96FN5 — 0.986 Q96FN5 →
CDC42BPG Serine/threonine-protein kinase MRCK gamma 0.985 landscape →
Q6PFD6 — 0.985 Q6PFD6 →
KIF18B Kinesin-like protein KIF18B 0.984 landscape →
Q8K330 — 0.983 Q8K330 →
Q5ZLK6 — 0.982 Q5ZLK6 →
TNK1 Non-receptor tyrosine-protein kinase TNK1 0.981 landscape →
Q66H85 — 0.981 Q66H85 →
Q9BRR9 — 0.981 Q9BRR9 →
Q80UW5 — 0.981 Q80UW5 →
Q4KLL9 — 0.980 Q4KLL9 →
Q9D2Z8 — 0.980 Q9D2Z8 →
P58660 — 0.980 P58660 →
O35787 — 0.980 O35787 →
P54777 — 0.979 P54777 →
Q8BHW9 — 0.979 Q8BHW9 →
Q9H8Y5 — 0.979 Q9H8Y5 →
MAP3K11 Mitogen-activated protein kinase kinase kinase 11 0.979 landscape →
Q1JPD6 — 0.979 Q1JPD6 →
Q9H6E5 — 0.978 Q9H6E5 →
Q99PT9 — 0.978 Q99PT9 →