Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15797818 | 0.93 | PPM1B (0.36) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL5750749 | 0.91 | ALDH1A1 (0.44) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL5750745 | 0.91 | ALDH1A1 (0.44) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL7266782 | 0.83 | ALDH1A1 (0.42) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL24198158 | 0.83 | PPM1B (0.37) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL417314 | 0.83 | ALDH1A1 (0.37) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL30242933 | 0.83 | PPM1B (0.37) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL31017143 | 0.83 | ALDH1A1 (0.37) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL1246430 | 0.83 | PPM1B (0.47) | PPM1BPTPN1PPP1CCMAPTCA12 | |
| SCHEMBL6900672 | 0.83 | PPM1B (0.47) | PPM1BPTPN1PPP1CCMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813500-B1 | Intermediates for the preparation of hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2813500-A1 | Intermediates for the preparation of hepatitis C virus inhibitors | Bristol-Myers Squibb Company (US) | 2014-12-17 | — | — | EP | disclosed |