Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 3/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13976552 | 1.00 | PYGM (0.46) | PYGMTK1P2RY6P2RY14TSHR | |
| SCHEMBL13976532 | 1.00 | PYGM (0.46) | PYGMTK1P2RY6P2RY14TSHR | |
| SCHEMBL12840822 | 0.90 | PYGM (0.50) | PYGMTK1P2RY6P2RY14BCHE | |
| SCHEMBL16307368 | 0.90 | PYGM (0.50) | PYGMTK1P2RY6P2RY14BCHE | |
| SCHEMBL13978280 | 0.90 | PYGM (0.50) | PYGMTK1P2RY6P2RY14BCHE | |
| SCHEMBL24359129 | 0.90 | PYGM (0.50) | PYGMTK1P2RY6P2RY14BCHE | |
| SCHEMBL13976551 | 0.90 | PYGM (0.50) | PYGMTK1P2RY6P2RY14BCHE | |
| SCHEMBL13976530 | 0.90 | PYGM (0.50) | PYGMTK1P2RY6P2RY14BCHE | |
| SCHEMBL16307197 | 0.90 | PYGM (0.50) | PYGMTK1P2RY6P2RY14BCHE | |
| SCHEMBL14702153 | 0.89 | PYGM (0.41) | PYGMTK1P2RY6P2RY14TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912318-B2 | Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids | UNIVERSITY OF IDAHO (US) | 2014-12-16 | — | — | US | disclosed |