Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16309032 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CHRM2CHRM1CHRM3SHBG | |
| SCHEMBL16109561 | 0.88 | ALDH1A1 (0.50) | ALDH1A1RIPK1MAPK1 | |
| SCHEMBL685573 | 0.88 | — | — | |
| SCHEMBL18355381 | 0.82 | ALDH1A1 (0.41) | ALDH1A1RIPK1MAPK1 | |
| SCHEMBL13849303 | 0.80 | ALDH1A1 (0.35) | ALDH1A1CHRM2CHRM1CHRM3SHBG | |
| SCHEMBL20002818 | 0.79 | LIPA (0.32) | — | |
| SCHEMBL24775454 | 0.79 | ALDH1A1 (0.43) | ALDH1A1RIPK1 | |
| SCHEMBL16133774 | 0.79 | ALDH1A1 (0.43) | ALDH1A1RIPK1 | |
| SCHEMBL11930043 | 0.79 | ALDH1A1 (0.43) | ALDH1A1RIPK1 | |
| SCHEMBL25131775 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CHRM2CHRM1CHRM3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894040-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2021-01-19 | — | — | US | disclosed |
| US-20200038385-A1 | S1P MODULATING AGENTS | BIOGEN IDEC MA INC. | 2020-02-06 | — | — | US | disclosed |
| US-10406144-B2 | SIP modulating agents | BIOGEN MA INC. (US) | 2019-09-10 | — | — | US | disclosed |
| US-10034869-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-10034869-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180028511-A1 | S1P MODULATING AGENTS | BIOGEN IDEC MA | 2018-02-01 | — | — | US | disclosed |
| US-20180028511-A1 | S1P MODULATING AGENTS | BIOGEN IDEC MA | 2018-02-01 | — | — | US | disclosed |
| US-9808449-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-9808449-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2017-11-07 | — | — | US | disclosed |
| EP-3150590-A1 | S1P MODULATING AGENTS | Biogen MA Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20160263093-A1 | S1P modulating agents | BIOGEN MA INC. | 2016-09-15 | — | — | US | disclosed |
| US-20160263093-A1 | S1P modulating agents | BIOGEN MA INC. | 2016-09-15 | — | — | US | disclosed |
| EP-2672823-B1 | S1P MODULATING AGENTS | BIOGEN MA INC (US) | 2016-08-24 | — | — | EP | disclosed |
| US-9340527-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9340527-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20140371209-A1 | S1P Modulating Agents | BIOGEN MA INC. | 2014-12-18 | — | — | US | disclosed |
| US-20140371209-A1 | S1P Modulating Agents | BIOGEN MA INC. | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038385-A1 | S1P MODULATING AGENTS | S1PR2, S1PR1, S1PR3 | ALDH1A1 2452/4885CHRM2 852/4885CHRM1 1184/4885 |
| US-20140371209-A1 | S1P Modulating Agents | S1PR2, S1PR1, S1PR3 | ALDH1A1 2436/4885CHRM2 606/4885CHRM1 794/4885 |
| US-10034869-B2 | S1P modulating agents | S1PR2, S1PR1, S1PR3 | ALDH1A1 2514/4885CHRM2 660/4885CHRM1 930/4885 |
| US-20180028511-A1 | S1P MODULATING AGENTS | S1PR2, S1PR1, S1PR3 | ALDH1A1 2452/4885CHRM2 852/4885CHRM1 1184/4885 |
| US-10406144-B2 | SIP modulating agents | S1PR2, S1PR1, S1PR3 | ALDH1A1 2802/4885CHRM2 586/4885CHRM1 787/4885 |
| US-10894040-B2 | S1P modulating agents | S1PR2, S1PR1, S1PR3 | ALDH1A1 2508/4885CHRM2 635/4885CHRM1 934/4885 |
| US-20160263093-A1 | S1P modulating agents | S1PR2, S1PR1, S1PR3 | ALDH1A1 2452/4885CHRM2 852/4885CHRM1 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.