Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632910 | 1.00 | KDM4E (0.40) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1630578 | 0.93 | MAPT (0.40) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1632079 | 0.93 | MAPT (0.40) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1632516 | 0.92 | MAPT (0.40) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1630868 | 0.92 | MAPT (0.40) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1632116 | 0.90 | MEN1 (0.41) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1630459 | 0.90 | MEN1 (0.41) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1631953 | 0.89 | MAPT (0.40) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1632287 | 0.88 | MAPT (0.39) | KDM4EL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1632426 | 0.88 | MAPT (0.39) | KDM4EL3MBTL1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932270-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2011-04-26 | — | — | US | disclosed |