Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | GLUL | P15104 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13581528 | 0.86 | NR3C1 (0.64) | NR3C1PGRGLUL | |
| SCHEMBL12917991 | 0.82 | NR3C1 (0.59) | NR3C1PGRGLUL | |
| SCHEMBL12956264 | 0.80 | NR3C1 (0.69) | NR3C1PGRGLUL | |
| SCHEMBL12956411 | 0.79 | NR3C1 (0.67) | NR3C1PGRGLUL | |
| SCHEMBL12956258 | 0.77 | NR3C1 (0.68) | NR3C1PGRGLUL | |
| SCHEMBL13581527 | 0.77 | NR3C1 (0.65) | NR3C1PGRGLUL | |
| SCHEMBL13581529 | 0.77 | NR3C1 (0.61) | NR3C1PGRGLUL | |
| SCHEMBL12956338 | 0.77 | NR3C1 (0.75) | NR3C1PGR | |
| SCHEMBL12956172 | 0.76 | NR3C1 (0.67) | NR3C1PGRGLUL | |
| SCHEMBL12956574 | 0.76 | NR3C1 (0.65) | NR3C1PGRGLUL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1617806-B1 | SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS | MERCK & CO INC (US) | 2009-11-04 | — | — | EP | disclosed |