Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16298502 | 0.91 | PDE5A (0.51) | PDE5A | |
| SCHEMBL8363069 | 0.79 | PDE5A (0.84) | PDE5A | |
| SCHEMBL16313301 | 0.76 | PDE5A (0.62) | PDE5A | |
| SCHEMBL16298501 | 0.73 | PDE5A (0.46) | PDE5A | |
| SCHEMBL8363071 | 0.71 | PDE5A (0.54) | PDE5A | |
| SCHEMBL8360081 | 0.68 | PDE5A (0.83) | PDE5A | |
| SCHEMBL16312817 | 0.65 | PDE5A (0.45) | PDE5A | |
| SCHEMBL14201493 | 0.62 | PDE5A (0.58) | PDE5A | |
| SCHEMBL5075690 | 0.59 | PDE5A (1.00) | PDE5A | |
| SCHEMBL8358726 | 0.58 | PDE5A (1.00) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790652-A1 | Polycyclic guanine phosphodiesterase V inhibitors | Schering Corporation (US) | 2007-05-30 | — | — | EP | disclosed |